HCID 19372249, compound → HCID 54267684, compound

HRID 129689Notes

Reaction equation

HRID 129689 reaction equation
[CH2:1]([N:8]1[C:16]2[C:11](=[CH:12][C:13]([O:17][CH2:18][C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)=[CH:14][CH:15]=2)[C:10]([CH:25]=O)=[CH:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[Br-].C1([PH+](C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1.[C:47](#[N:49])[CH3:48]>>[CH2:1]([N:8]1[C:16]2[C:11](=[CH:12][C:13]([O:17][CH2:18][C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)=[CH:14][CH:15]=2)[C:10]([CH:25]=[CH:48][C:47]#[N:49])=[CH:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 19372249HCID 19372249, compoundHCID 19372312HCID 19372312, compound

Product 1

HCID 54267684HCID 54267684, compound

Procedure

Following the procedure of Example 55, N-benzyl-5-benzyloxy-3-formylindole is treated with acetonitrile triphenylphosphonium bromide to give N-benzyl-5-benzyloxy-3-(2-cyanovinyl)indole.

Sources & evidence

ORD record
ord-bec108246a2147d88e7510754a22da10
Source dataset
uspto-grants-1995_11
Patent number
US05468898

Reaction notes

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