4-Chlororesorcinol → HCID 58913503, compound

Participants

Reaction Steps

This compounds was synthesised in the same manner as described above. 4-Chlororesorcinol (0.48 g, 3.31 mmol), [3,4-Bis-(3-cyano-propoxy)-phenyl]-acetic acid (1 g, 3.31 mmol), BF3Et2O (8 ml), PCl5 (1.03 g, 4.97 mmol), DMF (8 ml and 12 ml). The precipitate formed was filtered and re-crystallized from methanol to give 4-[4-(6-Chloro-7-hydroxy-4-oxo-4H-chromen-3-yl)-2-(3-cyano-propoxy)-phenoxy]-butyronitrile as a white solid (1.05 g, 72.5%); Rf 0.6 ethyl acetate/hexane (80/20)].

Provenance & Evidence