Sodium Azide → HCID 178437104, compound

HRID 129690Notes

Reaction equation

HRID 129690 reaction equation
[CH2:1]([N:8]1[C:16]2[C:11](=[CH:12][C:13]([O:17][CH2:18][C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)=[CH:14][CH:15]=2)[C:10]([CH:25]=[CH:26][C:27]#[N:28])=[CH:9]1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[N-:29]=[N+:30]=[N-:31].[Na+]>>[CH2:1]([N:8]1[C:16]2[C:11](=[CH:12][C:13]([O:17][CH2:18][C:19]3[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=3)=[CH:14][CH:15]=2)[C:10]([CH:25]=[CH:26][C:27]2[NH:31][N:30]=[N:29][N:28]=2)=[CH:9]1)[C:2]1[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=1

Participants

3

Reactant 2

HCID 33557Sodium AzideHCID 54267684HCID 54267684, compound

Product 1

HCID 178437104HCID 178437104, compound

Procedure

Following the procedure of Example 56, N-benzyl-5-benzyloxy-3-(2-cyanovinyl)indole is reacted with the sodium azide to give N-benzyl-5-benzyloxy-3-(2-tetrazol-5-ylvinyl)indole. (m.p. 178°-180° C. (dec.))

Sources & evidence

ORD record
ord-f9b43f4f0738497998fa6219a5f93e04
Source dataset
uspto-grants-1995_11
Patent number
US05468898

Reaction notes

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