Hydrazine hydrate (1:1) → HCID 178516581, compound

Participants

Reaction Steps

This compounds was synthesised in the same manner as described above. 6-Chloro-3-(4′-fluorobiphenyl-4-yl)-7-hydroxy-chromen-4-one (0.12 g, 0.33 mmol), Hydrazine hydrate (5 ml). The quenched reaction was extracted into ethyl acetate, washed (water), dried (MgSO4), and the solvent removed under vacuum to give 4-Chloro-6-[4-(4′-fluoro-biphenyl-4-yl)-1H-pyrazol-3-yl]-benzene-1,3-diol as a white solid (0.08 g, 63.7%).

Provenance & Evidence