3,3-Diphenylpropanol → (3,3-Diphenylpropane-1-yl)3-oxopentanoate

HRID 1297027Notes

Reaction equation

[O:1]=[C:2]([CH2:8][CH3:9])[CH2:3][C:4]([O:6][CH3:7])=[O:5].[C:10]1([CH:16]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[CH2:17]CO)[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1>C1(C)C=CC=CC=1>[C:10]1([CH:16]([C:20]2[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=2)[CH2:17][CH2:7][O:6][C:4](=[O:5])[CH2:3][C:2](=[O:1])[CH2:8][CH3:9])[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=1

Participants

Conditions

Temperature: 100 °C

Procedure

3.0 g (23.1 mg) of methyl 3-oxopentanoate and 4.9 g (23.1 mg) of 3,3-diphenylpropanol were stirred in 60 ml of toluene under heating at 100° C. overnight. Toluene was distilled out under reduced pressure to obtain the title compound.

Workup

distillationToluene was distilled out under reduced pressure

Sources & evidence

ORD record: ord-2a0c9a2429024a6ab9a63da3df2011d3
Source dataset: uspto-grants-2007_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07247645B2

Reaction notes

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