Acetaldehyde → HCID 69346062, compound

HRID 1297063Notes

Reaction equation

HRID 1297063 reaction equation
[CH:1](=O)[CH3:2].[NH2:4][C:5]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[CH:7][C:6]=1[S:13]([NH2:16])(=[O:15])=[O:14]>C(O)C>[CH3:12][O:11][C:8]1[CH:9]=[CH:10][C:5]2[NH:4][CH:1]([CH3:2])[NH:16][S:13](=[O:14])(=[O:15])[C:6]=2[CH:7]=1

Participants

4

Reactant 2

HCID 177AcetaldehydeHCID 112526652-Amino-5-methoxybenzenesulfonamide

Product 1

HCID 69346062HCID 69346062, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

829 μl of acetaldehyde are added to a suspension of 20 g of 2-amino-5-methoxy-benzenesulphonamide in 20 ml of anhydrous ethanol. The reaction mixture becomes homogeneous and is heated at reflux for 30 min. The ethanol is evaporated off in vacuo. The solid is taken up in ether and filtered off. The solid is taken up in 40 ml of ethanol, refluxed for 15 min. and allowed to return to ambient temperature. The expected product is obtained after filtration.

Workup

  1. temperatureis heated
  2. temperatureat reflux for 30 min
  3. customThe ethanol is evaporated off in vacuo
  4. filtrationfiltered off
  5. temperaturerefluxed for 15 min.
  6. customto return to ambient temperature

Sources & evidence

ORD record
ord-c8d9475db6304827ba7cb238c0606111
Source dataset
uspto-grants-2007_07
Patent number
US07250411B2

Reaction notes

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