HCID 9801579, compound → HCID 10295810, compound

Participants

Reaction Steps

By replacing 1-(2-benzo[b]thienyl)-7,8-diethoxy-3,5-dihydro-4H-2,3-benzodiazepin-4-one VIab in example IIIba by 1-(benzo[b]thienyl)-7,8-diethoxy-5-ethyl-3,5-dihydro-4H-2,3-benzodiazepin-4-one VIad and proceeding in the same manner, the abovenamed product is obtained. Yield: 70%. M: 79–81° C. 1H-NMR (200 MHz, CDCl3): d 1.07 (t, J=7.2, 3H, CH3), 1.42 (t, J=7.0, 3H, CH3), 1.52 (t, J=7.0, 3H, CH3), 1.92–2.47 (m, 2H, 5-CH2CH3), 2.96–3.04 (m, 1H, 5-H), 3.45 (s, 3H, 3-CH3), 3.99–4.25 (m, 4H, 3×OCH2CH3), 6.83 (s, 1H Ar), 7.13 (s, 1H Ar), 7.35–7.44 (m, 3H Ar), 7.72–7.90 (m, 2H Ar).

Provenance & Evidence