HCID 10224073, compound → HCID 10137937, compound

Participants

Reaction Steps

By replacing 1-(2-benzo[b]thienyl)-7,8-diethoxy-3,5-dihydro-4H-2,3-benzodiazepin-4-one VIab in example IIIba by 1-(2-benzo[b]thienyl)-7,8-diethoxy-5-n-propyl-3,5-dihydro-4H-2,3-benzodiazepin-4-one VIac and proceeding in the same manner, the abovenamed product is obtained. Yield: 34%. M: 61–63° C. 1H-NMR (200 MHz, CDCl3): d 1.01 (t, J=7.34, 3H, (CH2)2CH3), 1.39–4.55 (m, 8H, CH2CH2CH3+2×OCH2CH3), 1.75–2.42 (m, 2H, CH2CH2CH3), 3.04–3.11 (m, 1H, 5-H), 3.45 (s, 3H, 3-CH3), 3.99–4.23 (m, 4H, 2×OCH2CH3), 6.83 (s, 1H Ar), 7.12 (s, 1H Ar), 7.35–7.44 (m, 3H Ar), 7.72–7.89 (m, 2H Ar).

Provenance & Evidence