Glycine ethyl ester, hydrochloride → HCID 69463404, compound

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Reaction Steps

By replacing (2-amino-4,5-dimethoxyphenyl)(phenyl) methanone (XXIaa) in example XXIIaa by (2-amino-4,5-diethoxyphenyl)(phenyl)methanone (XXIag), and ethyl glycinate hydrochloride by methyl phenylanalilate hydrochloride, and proceeding in the same manner, the abovenamed product is obtained. Yield: 19%. M: 10–112° C. 1H-NMR (CDCl3, 200 MHz): d 1.38 (t, 3H, CH3), 1.55 (t, 3H, CH3), 3.61–3.66 (m, 2H, CH2), 3.82–3.98 (m, 3H, CH+OCH2), 4.18 (q, 2H, OCH2), 6.64 (s, 1H Ar), 6,75 (s, 1H Ar), 7.25–7.57 (m, 10H Ar), 8.65 (s, 1H exchangeable, —NH).

Provenance & Evidence