Glycine ethyl ester, hydrochloride → HCID 10221752, compound

Participants

Reaction Steps

By replacing (2-amino-4,5-dimethoxyphenyl)(phenyl)methanone (XXIaa) in example XXIIaa by (2-amino-4-ethoxy-5-methoxyphenyl)(phenyl)methanone XXIak, and ethyl glycinate hydrochloride by ethyl phenylglycinate hydrochloride, and proceeding in the same manner, the abovenamed product is obtained. Yield: 55%. M: 168–169° C. 1H-NMR (DMSO, 200 MHz): d 1.38–1.42 (m, 3H, CH3), 3.65 (s, 3H, OCH3), 3.98–4.18 (m, 2H, CH2), 4.76 (s, 1H, CH), 6.78 (s, 1H Ar), 6.88 (s, 1H Ar), 7.38–7.58 (m, 10H Ar), 10.49 (s, 1H, NH).

Provenance & Evidence