HCID 9858430, compound → HCID 10290924, compound

Participants

Reaction Steps

By replacing 5-(4-bromophenyl)-7,8-dimethoxy-1,3-dihydro-2H-1,4-benzodiazepin-2-one (XXIIaf) in example IIba by 7,8-diethoxy-5-phenyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one (XXIIag) and proceeding in the same manner, the abovenamed product is obtained. Yield: 28%. M: 116–118° C. 1H-NMR (CDCl3, 200 MHz): d 1.40 (t, 3H, CH3), 1.56 (t, 3H, CH3), 3.42 (s, 3H, NCH3), 3.97 (q, 2H, OCH2), 4.21 (q, 2H, OCH2), 4.33 (AB system, ? d=0.98 JAB=10.5, 2H, CH2), 6.74 (s, 1H Ar), 6.81 (s, 1H Ar), 7.42–7.70 (m, 5H Ar).

Provenance & Evidence