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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1297377Generated: October 31, 2026

Hydroxyamine hydrochloride → 6,7-dihydro-8(5H)-quinolinone oxime

https://huagongshe.com/reaction/1297377

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydroxyamine hydrochlorideHCID 443297—
Reactant6,7-Dihydro-5H-quinoline-8-oneHCID 11744777—
Product6,7-dihydro-8(5H)-quinolinone oximeHCID 13574218596%

Reaction Steps

According to the reported procedure (J. Het. Chem. 1978, 15, 249-251), 6,7-dihydro-5H-quinolin-8-one was reacted with hydroxylamine hydrochloride to afford the title compound (2.40 g, 96%) as a white solid after drying in vacuo: MS (ES) m/e 163 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07250424B2
Source datasetuspto-grants-2007_07
ORD IDord-0f59b6767fca47b7a714f9bc5c193f69
Source noteuspto-grants-2007_07