Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,3-dimethyl-1H-indole-2-carbaldehyde → 4-fluoro-1-methyl-3-(methylaminomethyl)-1H-indole
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,3-dimethyl-1H-indole-2-carbaldehyde | HCID 2771468 | — |
| 반응물 | 4-fluoro-1-methyl-1H-indole-3-carbaldehyde | HCID 22138994 | — |
| 반응물 | Methyl 2-((5-bromopyridin-2-yl)amino)acetate | HCID 22139049 | — |
| 생성물 | 4-fluoro-1-methyl-3-(methylaminomethyl)-1H-indole | HCID 22139151 | 77% |
반응 단계
According to the procedure of Preparation 11 (c), except substituting 4-fluoro-1-methyl-1H-indole-3-carboxaldehyde (0.3 g, 1.69 mmole) for the 1,3-dimethyl-1H-indole-2-carboxaldehyde, the title compound (0.2 g, 77%) was prepared as a viscous oil: MS (ES) m/e 193 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07250424B2 |
| 출처 데이터셋 | uspto-grants-2007_07 |
| ORD ID | ord-0f6f07f5d4d6443280572cfe75e41a60 |
| 출처 메모 | uspto-grants-2007_07 |