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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1297410Generated: October 30, 2026

Skatole → 5-Chloro-1-methylindole

https://huagongshe.com/reaction/1297410

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSkatoleHCID 6736—
Reactant5-ChloroindoleHCID 87110—
Product5-Chloro-1-methylindoleHCID 1085584391%

Reaction Steps

According to the procedure of Preparation 13 (a), except substituting 5-chloroindole for the 3-methylindole, the title compound (2.0 g, 91%) was obtained as an amber oil: MS (ES) m/e 166.0 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07250424B2
Source datasetuspto-grants-2007_07
ORD IDord-c2af4ab78b274e4eb3e12695bf63b448
Source noteuspto-grants-2007_07