HCID 6610570, compound → HCID 54281335, compound

HRID 129749Notes

Reaction equation

HRID 129749 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH:7]2[NH:11][C@H:10]([C:12]([OH:14])=O)[CH2:9][S:8]2)[CH:2]=1.[NH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][N:23]1[CH2:28][CH2:27][C:26](=[C:29]([C:36]2[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=2)[C:30]2[CH:35]=[CH:34][CH:33]=[CH:32][CH:31]=2)[CH2:25][CH2:24]1>>[C:30]1([C:29]([C:36]2[CH:41]=[CH:40][CH:39]=[CH:38][CH:37]=2)=[C:26]2[CH2:25][CH2:24][N:23]([CH2:22][CH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][NH:15][C:12]([C@@H:10]3[CH2:9][S:8][CH:7]([C:3]4[CH:2]=[N:1][CH:6]=[CH:5][CH:4]=4)[NH:11]3)=[O:14])[CH2:28][CH2:27]2)[CH:31]=[CH:32][CH:33]=[CH:34][CH:35]=1

Participants

3

Reactant 2

HCID 6610570HCID 6610570, compoundHCID 19370317HCID 19370317, compound

Product 1

HCID 54281335HCID 54281335, compoundYield 46%

Procedure

The title compound was prepared in a yield of 46% in a similar manner to that described in Example 17' by reacting 2-(3-pyridyl) thiazolidine-4(R)-carboxylic acid and 1-(7-aminoheptyl)-4-(diphenylmethylen) piperidine (prepared as described in Preparation 43').

Workup

  1. customprepared
  2. customas described in Preparation 43')

Sources & evidence

ORD record
ord-e1bd5192d1134547bf1361356c19647d
Source dataset
uspto-grants-1995_11
Patent number
US05470851

Reaction notes

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