Acetic Acid → HCID 44221072, compound

HRID 1297549Notes

Reaction equation

HRID 1297549 reaction equation
[CH3:1][C:2]1[CH:11]=[CH:10][CH:9]=[CH:8][C:3]=1[CH:4]=[CH:5][CH:6]=O.[CH3:12][C:13]([OH:15])=[O:14]>CC(OC(C)=O)=O>[C:13]([O:15][CH:1]1[C:2]2[C:3](=[CH:8][CH:9]=[CH:10][CH:11]=2)[CH:4]=[C:5]1[CH3:6])(=[O:14])[CH3:12]

Participants

4

Reactant 2

HCID 176Acetic AcidHCID 534274143-(2-Methylphenyl)-2-propenal

Product 1

HCID 44221072HCID 44221072, compoundYield 70%

Reagents, catalysts & solvents 1

HCID 7918Acetic AnhydrideSolvent2×

Procedure

Using the same experimental procedure as under a), 2-methylcinnamaldehyde (21 g, 0.14 mol) in AcOH (27 g), FeCl3·6H2O (6 ml of a 0.25 M solution in Ac2O, 1.5 mmol) in Ac2O (53 g) were reacted together. After a further 2 hours at reflux the cooled mixture was treated to the same workup and purification as before to provide the title compound

Workup

  1. customwere reacted together
  2. temperatureAfter a further 2 hours at reflux the cooled mixture
  3. additionwas treated to the same workup and purification as before

Sources & evidence

ORD record
ord-0ef4e653e8c44f6f83b6908ffce4f054
Source dataset
uspto-grants-2007_07
Patent number
US07250528B2

Reaction notes

Loading…