HCID 19370271, compound → HCID 19370317, compound

HRID 129761Notes

Reaction equation

HRID 129761 reaction equation
[C:1]1([C:7]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)=[C:8]2[CH2:13][CH2:12][N:11]([CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][C:20]#[N:21])[CH2:10][CH2:9]2)[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[H-].[Al+3].[Li+].[H-].[H-].[H-]>>[NH2:21][CH2:20][CH2:19][CH2:18][CH2:17][CH2:16][CH2:15][CH2:14][N:11]1[CH2:10][CH2:9][C:8](=[C:7]([C:22]2[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=2)[C:1]2[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=2)[CH2:13][CH2:12]1

Participants

3

Reactant 2

HCID 19370271HCID 19370271, compoundHCID 21226445Aluminium lithium hydride

Product 1

HCID 19370317HCID 19370317, compoundYield 91%

Procedure

The title compound was prepared in a yield of 91% in a similar manner to that described in Preparation 41' by reacting 4-(diphenylmethylene)-1-(6-cyanohexyl)-piperidine (prepared as described in Preparation 40') and lithium aluminum hydride.

Workup

  1. customdescribed in Preparation 41'
  2. customprepared

Sources & evidence

ORD record
ord-f77db94b947b4ec398a0f3f0afe129d3
Source dataset
uspto-grants-1995_11
Patent number
US05470851

Reaction notes

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