1H-Isoindole-1,3(2H)-dione, 2-(2-bromoethyl)- → HCID 19370342, compound
Reaction equation
Br[CH2:2][CH2:3][N:4]1[C:8](=[O:9])[C:7]2=[CH:10][CH:11]=[CH:12][CH:13]=[C:6]2[C:5]1=[O:14].[C:15]1([C:21]([C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)=[C:22]2[CH2:27][CH2:26][NH:25][CH2:24][CH2:23]2)[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1>>[C:15]1([C:21]([C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)=[C:22]2[CH2:23][CH2:24][N:25]([CH2:2][CH2:3][N:4]3[C:8](=[O:9])[C:7]4=[CH:10][CH:11]=[CH:12][CH:13]=[C:6]4[C:5]3=[O:14])[CH2:26][CH2:27]2)[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=1Participants
3
Procedure
The title compound was prepared in a yield of 88% in a similar manner to that described in Preparation 1' by reacting N-(2-bromoethyl)phthalimide and 4-diphenylmethylenepiperidine.
Workup
- customdescribed in Preparation 1'
Sources & evidence
- ORD record
- ord-6c0c620700b14d88b08c4a88a6f0f656
- Source dataset
- uspto-grants-1995_11
- Patent number
- US05470851
Reaction notes
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