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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1297641Generated: October 30, 2026

2-Pyridinemethanamine → HCID 178466945, compound

https://huagongshe.com/reaction/1297641

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-PyridinemethanamineHCID 19509—
ReactantDiisopropylethylamineHCID 81531—
Reactant4-Ethoxy-6-[2-methylsulfanyl-4-oxo-4h-thiazol-(5z)-ylidenemethyl]-quinoline-3-carbonitrileHCID 58585820—
ProductHCID 178466945HCID 178466945—

Reaction Steps

Similar procedure as described in example 14h was used, starting from 4-ethoxy-6-[2-methylsulfanyl-4-oxo-4H-thiazol-(5Z)-ylidenemethyl]-quinoline-3-carbonitrile (example 14g), (pyridin-2-ylmethyl)-amine and DIEA to give 4-ethoxy-6-[4-oxo-2-[(pyridin-2-ylmethyl)-amino]-4H-thiazol-(5Z)-ylidenemethyl]-quinoline-3-carbonitrile. LC-MS m/e 416 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07250515B2
Source datasetuspto-grants-2007_07
ORD IDord-0695224cd1b442dc8fa68c733552ee2d
Source noteuspto-grants-2007_07