HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenylethanolamine → HCID 178466954, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenylethanolamine | HCID 1000 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 4-Ethoxy-6-[2-methylsulfanyl-4-oxo-4h-thiazol-(5z)-ylidenemethyl]-quinoline-3-carbonitrile | HCID 58585820 | — |
| Product | HCID 178466954 | HCID 178466954 | — |
Reaction Steps
Similar procedure as described in example 14h was used, starting from 4-ethoxy-6-[2-methylsulfanyl-4-oxo-4H-thiazol-(5Z)-ylidenemethyl]-quinoline-3-carbonitrile (example 14g), 2-hydroxy-2-phenyl-ethylamine and DIEA to give 4-ethoxy-6-[2-(2-hydroxy-2-phenyl-ethylamino)-4-oxo-4H-thiazol-(5Z)-ylidenemethyl]-quinoline-3-carbonitrile. LC-MS m/e 445 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07250515B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-7633f2460bf24f5db6bf54bbbb9a6848 |
| Source note | uspto-grants-2007_07 |