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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1297646Generated: October 30, 2026

Diisopropylethylamine → HCID 178466948, compound

https://huagongshe.com/reaction/1297646

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDiisopropylethylamineHCID 81531—
Reactant2-PyrimidinemethanamineHCID 4658047—
Reactant4-Ethoxy-6-[2-methylsulfanyl-4-oxo-4h-thiazol-(5z)-ylidenemethyl]-quinoline-3-carbonitrileHCID 58585820—
ProductHCID 178466948HCID 178466948—

Reaction Steps

Similar procedure as described in example 14h was used, starting from 4-ethoxy-6-[2-methylsulfanyl-4-oxo-4H-thiazol-(5Z)-ylidenemethyl]-quinoline-3-carbonitrile (example 14g), pyrimidin-2-ylmethylamine and DIEA to give 4-ethoxy-6-[4-oxo-2-[(pyrimidin-2-ylmethyl)-amino]-4H-thiazol-(5Z)-ylidenemethyl]-quinoline-3-carbonitrile. LC-MS m/e 417 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07250515B2
Source datasetuspto-grants-2007_07
ORD IDord-5d868e549d3d460eb48670fb83c11eaa
Source noteuspto-grants-2007_07