Sodium Acetate → HCID 11639249, compound

HRID 1297662Notes

Reaction equation

HRID 1297662 reaction equation
[C:1]([S:5][C:6]1[C:15]2[C:10](=[CH:11][CH:12]=[C:13]([CH:16]=O)[CH:14]=2)[N:9]=[CH:8][C:7]=1[C:18]#[N:19])([CH3:4])([CH3:3])[CH3:2].COC1C=CC(/C=[C:35]2/[C:36]([NH:38][C:39]([S:41]/2)=[NH:40])=[O:37])=CC=1OC1CCCC1.C([O-])(=O)C.[Na+]>C(O)(=O)C>[NH2:40][C:39]1[S:41]/[C:35](=[CH:16]\[C:13]2[CH:14]=[C:15]3[C:10](=[CH:11][CH:12]=2)[N:9]=[CH:8][C:7]([C:18]#[N:19])=[C:6]3[S:5][C:1]([CH3:4])([CH3:3])[CH3:2])/[C:36](=[O:37])[N:38]=1

Participants

5

Reactant 3

HCID 517045Sodium AcetateHCID 58585785HCID 58585785, compoundHCID 137629131(5Z)-5-[(3-cyclopentyloxy-4-methoxyphenyl)methylidene]-2-imino-1,3-thiazolidin-4-one

Product 1

HCID 11639249HCID 11639249, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Similar procedure as described in example 38 was used, starting from 4-tert-butylsulfanyl-6-formyl-quinoline-3-carbonitrile (example 39b), pseudothiohydantoin, sodium acetate and acetic acid to give 6-[2-amino-4-oxo-4H-thiazol-(5Z)-ylidenemethyl]-4-tert-butylsulfanyl-quinoline-3-carbonitrile. LC-MS m/e 369 (MH+).

Sources & evidence

ORD record
ord-eceac27a5c0a4f219f66808d2136fa13
Source dataset
uspto-grants-2007_07
Patent number
US07250515B2

Reaction notes

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