HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Propanethiol → 4-Isopropylsulfanyl-6-iodo-quinoline-3-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Propanethiol | HCID 6364 | — |
| Reactant | Diisopropylethylamine | HCID 81531 | — |
| Reactant | 4-Chloro-6-iodoquinoline-3-carbonitrile | HCID 22466769 | — |
| Product | 4-Isopropylsulfanyl-6-iodo-quinoline-3-carbonitrile | HCID 58585828 | — |
Reaction Steps
Similar procedure as described in example 39a was used, starting from 4-chloro-6-iodo-quinoline-3-carbonitrile (example 14c), DIEA and 2-propanethiol to give 4-isopropylsulfanyl-6-iodo-quinoline-3-carbonitrile. LC-MS m/e 355 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07250515B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-52c844d576304abf8d1f918f26da0874 |
| Source note | uspto-grants-2007_07 |