Sodium Acetate → HCID 11690950, compound

HRID 1297664Notes

Reaction equation

HRID 1297664 reaction equation
[CH:1]([S:4][C:5]1[C:14]2[C:9](=[CH:10][CH:11]=[C:12]([CH:15]=O)[CH:13]=2)[N:8]=[CH:7][C:6]=1[C:17]#[N:18])([CH3:3])[CH3:2].COC1C=CC(/C=[C:34]2/[C:35]([NH:37][C:38]([S:40]/2)=[NH:39])=[O:36])=CC=1OC1CCCC1.C([O-])(=O)C.[Na+]>C(O)(=O)C>[NH2:39][C:38]1[S:40]/[C:34](=[CH:15]\[C:12]2[CH:13]=[C:14]3[C:9](=[CH:10][CH:11]=2)[N:8]=[CH:7][C:6]([C:17]#[N:18])=[C:5]3[S:4][CH:1]([CH3:3])[CH3:2])/[C:35](=[O:36])[N:37]=1

Participants

5

Reactant 3

HCID 517045Sodium AcetateHCID 58585835HCID 58585835, compoundHCID 137629131(5Z)-5-[(3-cyclopentyloxy-4-methoxyphenyl)methylidene]-2-imino-1,3-thiazolidin-4-one

Product 1

HCID 11690950HCID 11690950, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Similar procedure as described in example 38 was used, starting from 4-isopropylsulfanyl-6-formyl-quinoline-3-carbonitrile (example 40b), pseudothiohydantoin, sodium acetate and acetic acid to give 6-[2-amino-4-oxo-4H-thiazol-(5Z)-ylidenemethyl]-4-isopropylsulfanyl-quinoline-3-carbonitrile. LC-MS m/e 355 (MH+).

Sources & evidence

ORD record
ord-af6180c3c00545038cd30b60e7a7af9e
Source dataset
uspto-grants-2007_07
Patent number
US07250515B2

Reaction notes

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