Ethyl cyanoacetate → 2-Propenoic acid, 2-cyano-3-ethoxy-, ethyl ester

Participants

Reaction Conditions

Reaction Steps

The mixture of triethyl orthoformate (33.3 mL, 0.2 mol) and ethyl cyanoacetate (21.3 mL, 0.2 mol) in acetic anhydride (80 mL) was heated at 150-160° C. for 5 h. After cooling to room temperature, the solvent was removed under reduced pressure to give ethyl 2-cyano-3-ethoxyacrylate as a yellow solid (28.5 g, 84%).

Provenance & Evidence