HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium borohydride → 6-Hydroxymethyl-4-butyl-1,4-dihydro-quinoline-3-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium borohydride | HCID 4148881 | — |
| Reactant | 3-Cyano-4-butyl-quinoline-6-carboxylic acid ethyl ester | HCID 58585812 | — |
| Product | 6-Hydroxymethyl-4-butyl-1,4-dihydro-quinoline-3-carbonitrile | HCID 58585834 | — |
Reaction Steps
Similar procedure as described in example 46e was used, starting from 3-cyano-4-butyl-quinoline-6-carboxylic acid ethyl ester (example 49a) and lithium borohydride to give 6-hydroxymethyl-4-butyl-1,4-dihydro-quinoline-3-carbonitrile as a yellow solid. LC-MS m/e 243 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07250515B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-6f541a84264d473ba37ef42fbe4e72e9 |
| Source note | uspto-grants-2007_07 |