Sodium Acetate → HCID 11660135, compound

HRID 1297687Notes

Reaction equation

HRID 1297687 reaction equation
[CH2:1]([S:3][C:4]1[C:13]2[C:8](=[CH:9][CH:10]=[C:11]([CH:14]=O)[CH:12]=2)[N:7]=[CH:6][C:5]=1[C:16]#[N:17])[CH3:2].COC1C=CC(/C=[C:33]2/[C:34]([NH:36][C:37]([S:39]/2)=[NH:38])=[O:35])=CC=1OC1CCCC1.C([O-])(=O)C.[Na+]>C(O)(=O)C>[NH2:38][C:37]1[S:39]/[C:33](=[CH:14]\[C:11]2[CH:12]=[C:13]3[C:8](=[CH:9][CH:10]=2)[N:7]=[CH:6][C:5]([C:16]#[N:17])=[C:4]3[S:3][CH2:1][CH3:2])/[C:34](=[O:35])[N:36]=1

Participants

5

Reactant 3

HCID 517045Sodium AcetateHCID 58585826HCID 58585826, compoundHCID 137629131(5Z)-5-[(3-cyclopentyloxy-4-methoxyphenyl)methylidene]-2-imino-1,3-thiazolidin-4-one

Product 1

HCID 11660135HCID 11660135, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Similar procedure as described in example 38 was used, starting from 4-ethylsulfanyl-6-formyl-quinoline-3-carbonitrile (example 54b), pseudothiohydantoin, sodium acetate and acetic acid to give 6-[2-amino-4-oxo-4H-thiazol-(5Z)-ylidenemethyl]-4-ethylsulfanyl-quinoline-3-carbonitrile. LC-MS m/e 341 (MH+).

Sources & evidence

ORD record
ord-dc7cc18ee6b14f24a0369cc6ca9c023e
Source dataset
uspto-grants-2007_07
Patent number
US07250515B2

Reaction notes

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