HuagongsheHuagongshe Chemistry Print Report · For research reference only
Lithium borohydride → 4-Cyclopropyl-6-hydroxymethyl-1,4-dihydro-quinoline-3-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Lithium borohydride | HCID 4148881 | — |
| Reactant | HCID 58585833 | HCID 58585833 | — |
| Product | 4-Cyclopropyl-6-hydroxymethyl-1,4-dihydro-quinoline-3-carbonitrile | HCID 58585784 | — |
Reaction Steps
Similar procedure as described in example 46e was used, starting from 3-cyano-4-cyclopropyl-quinoline-6-carboxylic acid ethyl ester (example 57a) and lithium borohydride to give 4-cyclopropyl-6-hydroxymethyl-1,4-dihydro-quinoline-3-carbonitrile as a yellow solid. LC-MS m/e 227 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07250515B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-86e0ae3571864844ac6331b4ad45d1eb |
| Source note | uspto-grants-2007_07 |