HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Cyclopropyl-6-hydroxymethyl-1,4-dihydro-quinoline-3-carbonitrile → 4-Cyclopropyl-6-formyl-quinoline-3-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Cyclopropyl-6-hydroxymethyl-1,4-dihydro-quinoline-3-carbonitrile | HCID 58585784 | — |
| Catalyst | HCID 178418406 | HCID 178418406 | — |
| Product | 4-Cyclopropyl-6-formyl-quinoline-3-carbonitrile | HCID 58585816 | — |
Reaction Steps
Similar procedure as described in example 46f was used, starting from 4-cyclopropyl-6-hydroxymethyl-1,4-dihydro-quinoline-3-carbonitrile (example 57b) and manganese dioxide to give 4-cyclopropyl-6-formyl-quinoline-3-carbonitrile as a white solid. LC-MS m/e 223 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07250515B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-f37ba696a523476fb9b55f6b74d936ea |
| Source note | uspto-grants-2007_07 |