HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydride → 6-Hydroxymethyl-4-phenyl-quinoline-3-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydride | HCID 166653 | — |
| Reactant | HCID 58585788 | HCID 58585788 | — |
| Product | 6-Hydroxymethyl-4-phenyl-quinoline-3-carbonitrile | HCID 58585799 | — |
Reaction Steps
Similar procedure as described in example 61h was used, starting from 3-cyano-4-phenyl-quinoline-6-carboxylic acid ethyl ester (example 62a), and diisobutylaminum hydride to give 6-hydroxymethyl-4-phenyl-quinoline-3-carbonitrile. LC-MS m/e 261 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07250515B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-01d34b7d3d0d4eb084f36e44b4c1959d |
| Source note | uspto-grants-2007_07 |