HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Carbonate → HCID 58585865, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Carbonate | HCID 10340 | — |
| Reactant | 3-Pyridinylboronic acid | HCID 2734378 | — |
| Reactant | 4-Chloro-3-cyano-6-quinolinecarboxylic acid ethyl ester | HCID 58585823 | — |
| Catalyst | HCID 178418397 | HCID 178418397 | — |
| Product | HCID 58585865 | HCID 58585865 | — |
Reaction Steps
Similar procedure as described in example 61g was used, starting from 4-chloro-3-cyano-quinoline-6-carboxylic acid ethyl ester (example 46c), pyridine-3-boronic acid, tetrakis(triphenylphosphine)palladium(0), and sodium carbonate solution to give 3-cyano-4-pyridin-3-yl-quinoline-6-carboxylic acid ethyl ester. LC-MS m/e 304 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07250515B2 |
| Source dataset | uspto-grants-2007_07 |
| ORD ID | ord-f501b40115d643a884c735075ab090d9 |
| Source note | uspto-grants-2007_07 |