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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1297724Generated: October 29, 2026

Sodium Acetate → HCID 178446965, compound

https://huagongshe.com/reaction/1297724

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium AcetateHCID 517045—
Reactant6-Formyl-4-((tetrahydro-2H-pyran-4-yl)oxy)quinoline-3-carbonitrileHCID 58585783—
ReactantHCID 178516935HCID 178516935—
SolventAcetic AcidHCID 176—
ProductHCID 178446965HCID 178446965—

Reaction Steps

Similar procedure as described in example 28c was used, starting from 6-formyl-4-(tetrahydro-pyran-4-yloxy)-quinoline-3-carbonitrile (example 64b), 2-cyclopropylamino-thiazol-4-one (example 37c), sodium acetate and acetic acid to give 6-[2-cyclopropylamino-4-oxo-4H-thiazol-(5Z)-ylidenemethyl]-4-(1-ethyl-propoxy)-quinoline-3-carbonitrile. LC-MS m/e 407 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07250515B2
Source datasetuspto-grants-2007_07
ORD IDord-b16fcc5aa7434109bb12fb9dc8b1750c
Source noteuspto-grants-2007_07