HRID1297726

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID517045

Sodium Acetate

C2H3NaO2

HCID58585871

未命名化合物

HCID178516935

未命名化合物

PRODUCTS

生成物

$结构：CC(C)(C)COc1c(C#N)cnc2ccc(/C=C3\SC(NC4CC4)=NC3=O)cc12$

HCID178446964

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID176

Acetic Acid

C2H4O2

PROCEDURE

实验过程

Similar procedure as described in example 28c was used, starting from 4-(2,2-dimethyl-propoxy)-6-formyl-quinoline-3-carbonitrile (example 67b), 2-cyclopropylamino-thiazol-4-one (example 37c), sodium acetate and acetic acid to give 6-[2-cyclopropylamino-4-oxo-4H-thiazol-(5Z)-ylidenemethyl]-4-(2,2-dimethyl-propoxy)-quinoline-3-carbonitrile. LC-MS m/e 407 (MH+).