Sodium Acetate → HCID 11646003, compound

HRID 1297731Notes

Reaction equation

HRID 1297731 reaction equation
C([C:3]1[CH:4]=[C:5]2C(=[CH:11][CH:12]=1)[N:9]=[CH:8][C:7]([C:13]#[N:14])=[C:6]2CCC)=O.CO[C:20]1[CH:21]=[CH:22][C:23](/[CH:32]=[C:33]2/[C:34]([NH:36][C:37]([S:39]/2)=[NH:38])=[O:35])=[CH:24][C:25]=1OC1CCCC1.C([O-])(=O)C.[Na+]>C(O)(=O)C>[NH2:38][C:37]1[S:39]/[C:33](=[CH:32]\[C:23]2[CH:24]=[C:25]3[C:20](=[CH:21][CH:22]=2)[N:9]=[CH:8][C:7]([C:13]#[N:14])=[C:6]3[CH2:5][CH2:4][CH2:3][CH2:12][CH3:11])/[C:34](=[O:35])[N:36]=1

Participants

5

Reactant 3

HCID 517045Sodium AcetateHCID 58585847HCID 58585847, compoundHCID 137629131(5Z)-5-[(3-cyclopentyloxy-4-methoxyphenyl)methylidene]-2-imino-1,3-thiazolidin-4-one

Product 1

HCID 11646003HCID 11646003, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Similar procedure as described in example 28c was used, starting from 6-formyl-4-propyl-quinoline-3-carbonitrile (example 72c), pseudothiohydantoin, sodium acetate and acetic acid to give 6-[2-amino-4-oxo-4H-thiazol-(5Z)-ylidenemethyl]-4-pentyl-quinoline-3-carbonitrile. LC-MS m/e 351 (MH+).

Sources & evidence

ORD record
ord-c10e65a20f3c48c49ede4cf1389e34be
Source dataset
uspto-grants-2007_07
Patent number
US07250515B2

Reaction notes

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