Sodium Acetate → HCID 11565572, compound

HRID 1297733Notes

Reaction equation

HRID 1297733 reaction equation
[CH:1]([C:3]1[CH:4]=[C:5]2[C:10](=[CH:11][CH:12]=1)[N:9]=[CH:8][C:7]([C:13]#[N:14])=[C:6]2[CH3:15])=O.COC1C=CC(/C=[C:31]2/[C:32]([NH:34][C:35]([S:37]/2)=[NH:36])=[O:33])=CC=1OC1CCCC1.C([O-])(=O)C.[Na+]>C(O)(=O)C>[NH2:36][C:35]1[S:37]/[C:31](=[CH:1]\[C:3]2[CH:4]=[C:5]3[C:10](=[CH:11][CH:12]=2)[N:9]=[CH:8][C:7]([C:13]#[N:14])=[C:6]3[CH3:15])/[C:32](=[O:33])[N:34]=1

Participants

5

Reactant 3

HCID 517045Sodium AcetateHCID 58585803HCID 58585803, compoundHCID 137629131(5Z)-5-[(3-cyclopentyloxy-4-methoxyphenyl)methylidene]-2-imino-1,3-thiazolidin-4-one

Product 1

HCID 11565572HCID 11565572, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

Similar procedure as described in example 28c was used, starting from 6-formyl-4-methyl-quinoline-3-carbonitrile (example 73c), pseudothiohydantoin, sodium acetate and acetic acid to give 6-[2-amino-4-oxo-4H-thiazol-(5Z)-ylidenemethyl]-4-methyl-quinoline-3-carbonitrile. LC-MS m/e 295 (MH+).

Sources & evidence

ORD record
ord-26bf6f338c2e4a6aafceecd464791c28
Source dataset
uspto-grants-2007_07
Patent number
US07250515B2

Reaction notes

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