反应详情

2.2 g of trichloromethanesulfenyl chloride are introduced into a solution of 2 g of 2,4,6-trimethyl benzamidine in 16 ml of dichloromethane under an inert atmosphere at about -20° C., followed by the slow addition of 2 g of NaOH dissolved in 3.2 ml of water at about -10° C. After I hour at about -5° C., the precipitate formed is isolated and the organic phase is separated and washed with 6 ml of water. After being dried over K2CO3, it is concentrated under reduced pressure to give 2.8 g of the desired product in the form of an oil, which may be used without purification.

1. customAfter I hour at about -5° C., the precipitate formed
2. customis isolated
3. customthe organic phase is separated
4. washwashed with 6 ml of water
5. dry with materialAfter being dried over K2CO3, it
6. concentrationis concentrated under reduced pressure