p-(2-Oxo,3-bromo propyloxy)-benzoic acid → 8-[3-[(p-Carboxy)-phenoxy]-2-oxo-propylthio]-adenine

HRID 129822Notes

Reaction equation

HRID 129822 reaction equation
[SH:1][C:2]1[NH:10][C:9]2[C:4](=[N:5][CH:6]=[N:7][C:8]=2[NH2:11])[N:3]=1.[O:12]=[C:13]([CH2:25]Br)[CH2:14][O:15][C:16]1[CH:24]=[CH:23][C:19]([C:20]([OH:22])=[O:21])=[CH:18][CH:17]=1>>[C:20]([C:19]1[CH:23]=[CH:24][C:16]([O:15][CH2:14][C:13](=[O:12])[CH2:25][S:1][C:2]2[NH:10][C:9]3[C:4](=[N:5][CH:6]=[N:7][C:8]=3[NH2:11])[N:3]=2)=[CH:17][CH:18]=1)([OH:22])=[O:21]

Participants

3

Reactant 2

HCID 19370535p-(2-Oxo,3-bromo propyloxy)-benzoic acidHCID 178508691HCID 178508691, compound

Product 1

HCID 543413048-[3-[(p-Carboxy)-phenoxy]-2-oxo-propylthio]-adenine

Procedure

From 8-mercapto-adenine and p-(2-oxo,3-bromo propyloxy)-benzoic acid.

Sources & evidence

ORD record
ord-25379fce7f1340508f54a781d06d45b9
Source dataset
uspto-grants-1995_11
Patent number
US05470858

Reaction notes

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