HCID 86749116, compound → HCID 23364135, compound

HRID 129841Notes

Reaction equation

HRID 129841 reaction equation
C(OC([N:11]([C:20]1[CH:25]=[C:24]([CH3:26])[CH:23]=[C:22]([CH3:27])[N:21]=1)[CH2:12][C:13]([NH:15][CH2:16][C:17]([NH2:19])=[O:18])=[O:14])=O)C1C=CC=CC=1>CO.[Pd]>[CH3:26][C:24]1[CH:23]=[C:22]([CH3:27])[N:21]=[C:20]([NH:11][CH2:12][C:13]([NH:15][CH2:16][C:17]([NH2:19])=[O:18])=[O:14])[CH:25]=1

Participants

4

Reactant 1

HCID 86749116HCID 86749116, compound

Product 1

HCID 23364135HCID 23364135, compound

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 887MethanolSolvent

Procedure

1 g (2.6 mmol) of the product of Example 24 is dissolved in 60 ml of methanol. Palladium-on-carbon is added and the whole is stirred under a hydrogen atmosphere. Filtration is then carried out, the methanol is evaporated and the title product is recovered.

Workup

  1. filtrationFiltration
  2. customthe methanol is evaporated
  3. customthe title product is recovered

Sources & evidence

ORD record
ord-546ff11f9dcb4e75a7c99cee3c6aa092
Source dataset
uspto-grants-1995_11
Patent number
US05470864

Reaction notes

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