HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrogen Bromide → 2-Bromo-4-fluoro-6-nitroaniline
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrogen Bromide | HCID 260 | — |
| Reactant | Bromine | HCID 24408 | — |
| Reactant | 4-Fluoro-2-nitroaniline | HCID 67769 | — |
| Solvent | Water | HCID 962 | — |
| Product | 2-Bromo-4-fluoro-6-nitroaniline | HCID 292004 | — |
Reaction Conditions
| Temperature | 7 °C |
|---|
Reaction Steps
Mix 4-fluoro-2-nitroaniline (15.6 g, 0.1 mol) in water (400 mL) and add 48% hydrobromic acid (1kg). Add bromine (16 g, 0.1 mol) with stirring and stir for 1 hour. Dilute to 2L and cool to 7° C. Filter, wash with water and dry to give 4-fluoro-2-bromo-6-nitroaniline.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05470870 |
| Source dataset | uspto-grants-1995_11 |
| ORD ID | ord-aa8ecdb05e154ce489facf8685c73331 |
| Source note | uspto-grants-1995_11 |