HCID 59730487, compound → HCID 59730484, compound

HRID 130314Notes

Reaction equation

HRID 130314 reaction equation
O=C1C2C(=CC=CC=2)C2CC3C(C(O)=O)=CC=CC=3C=2N1.[O:22]=[C:23]1[C:32]2[C:27](=[CH:28][CH:29]=[CH:30][CH:31]=2)[C:26]2[CH2:33][C:34]3[CH:35]=[C:36]([C:40]([O:42]C)=[O:41])[CH:37]=[CH:38][C:39]=3[C:25]=2[NH:24]1>>[O:22]=[C:23]1[C:32]2[C:27](=[CH:28][CH:29]=[CH:30][CH:31]=2)[C:26]2[CH2:33][C:34]3[CH:35]=[C:36]([C:40]([OH:42])=[O:41])[CH:37]=[CH:38][C:39]=3[C:25]=2[NH:24]1

Participants

3

Reactant 2

HCID 59730487HCID 59730487, compoundHCID 59730490HCID 59730490, compound

Product 1

HCID 59730484HCID 59730484, compound

Procedure

The above compound was made according to the procedure for preparing 5,6-dihydro-5-oxo-11-H-indeno[1,2-c]isoquinoline-10-carboxylic acid (18b), but using Compound 18a in place of Compound 17a. 1H NMR (DMSO-d6): δ 12.34 (s, 1H); 8.24 (d, J=8.1 Hz, 1H); 8.20 (d, J=7.5 Hz 1H); 7.88 (d, J=7.8 Hz, 1H); 7.77 (m, 2H); 7.54 (d, J=7.8 Hz, 2H); 7.49 (d, J=8.1 Hz, 1H); 4.18 (s, 2H).

Sources & evidence

ORD record
ord-4c603485920b4de08646368c3921c4fe
Source dataset
uspto-grants-2008_06
Patent number
US07381722B2

Reaction notes

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