Bromine → [3-(2-Bromo-acetyl)-phenoxy]-phenyl-acetic acid methyl ester
Reaction equation
[CH3:1][O:2][C:3](=[O:21])[CH:4]([O:11][C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([C:18](=[O:20])[CH3:19])[CH:13]=1)[C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1.[Br:22]Br>>[CH3:1][O:2][C:3](=[O:21])[CH:4]([O:11][C:12]1[CH:17]=[CH:16][CH:15]=[C:14]([C:18](=[O:20])[CH2:19][Br:22])[CH:13]=1)[C:5]1[CH:6]=[CH:7][CH:8]=[CH:9][CH:10]=1Participants
3
Procedure
[3-(2-Bromo-acetyl)-phenoxy]-phenyl-acetic acid methyl ester was synthesized from (3-acetyl-phenoxy)-phenyl-acetic acid methyl ester and bromine as described in example 31.
Sources & evidence
- ORD record
- ord-b613c36cd5c44357a492d9ce233d589f
- Source dataset
- uspto-grants-2008_06
- Patent number
- US07381736B2
Reaction notes
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