4-Iodobenzenesulfonyl chloride → HCID 69197436, compound

HRID 130459Notes

Reaction equation

HRID 130459 reaction equation
[CH3:1][C@H:2]1[NH:7][C@@H:6]([CH3:8])[CH2:5][N:4]([C:9]2[C:10]([O:18][CH3:19])=[CH:11][C:12]([O:16][CH3:17])=[C:13]([CH:15]=2)[NH2:14])[CH2:3]1.[I:20][C:21]1[CH:26]=[CH:25][C:24]([S:27](Cl)(=[O:29])=[O:28])=[CH:23][CH:22]=1>>[CH3:1][C@H:2]1[NH:7][C@@H:6]([CH3:8])[CH2:5][N:4]([C:9]2[C:10]([O:18][CH3:19])=[CH:11][C:12]([O:16][CH3:17])=[C:13]([NH:14][S:27]([C:24]3[CH:25]=[CH:26][C:21]([I:20])=[CH:22][CH:23]=3)(=[O:29])=[O:28])[CH:15]=2)[CH2:3]1

Participants

3

Reactant 2

HCID 73994-Iodobenzenesulfonyl chlorideHCID 69195867HCID 69195867, compound

Product 1

HCID 69197436HCID 69197436, compound

Procedure

The title compound was prepared from 5-(cis-3,5-dimethyl-1-piperazinyl)-2,4-bis(methyloxy)aniline (D25) and 4-iodobenzenesulfonyl chloride using a similar procedure to that described for Example 81. MS (ES+) m/e 532 [M+H]+.

Sources & evidence

ORD record
ord-93525b752fb9412ca24f0672c6cc4e95
Source dataset
uspto-grants-2008_06
Patent number
US07381728B2

Reaction notes

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