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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 13046Generated: October 30, 2026

Pivaloyl chloride → HCID 25011854, compound

https://huagongshe.com/reaction/13046

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPivaloyl chlorideHCID 62493—
Reactant(1S,2R)-1-{[1-(4-fluorophenyl)-1H-indazol-5-yl]oxy}-1-phenylpropan-2-amineHCID 66812640—
ProductHCID 25011854HCID 25011854—

Reaction Steps

Prepared as described in Example 1 using (1S,2R)-1-{[1-(4-fluorophenyl)-1H-indazol-5-yl]oxy}-1-phenylpropan-2-amine (1a, 18 mg, 50 μmol) and 2,2-dimethylpropanoyl chloride (18 mg, 150 μmol). Yield 17 mg (74%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07728030B2
Source datasetuspto-grants-2010_06
ORD IDord-6a4691481cfc4b44a42c5f0318c571f8
Source noteuspto-grants-2010_06