2-Thiopheneboronic acid → HCID 59007089, compound

HRID 130460Notes

Reaction equation

HRID 130460 reaction equation
[CH3:1][C@H:2]1[NH:7][C@@H:6]([CH3:8])[CH2:5][N:4]([C:9]2[C:10]([O:28][CH3:29])=[CH:11][C:12]([O:26][CH3:27])=[C:13]([NH:15][S:16]([C:19]3[CH:24]=[CH:23][C:22](I)=[CH:21][CH:20]=3)(=[O:18])=[O:17])[CH:14]=2)[CH2:3]1.[S:30]1[CH:34]=[CH:33][CH:32]=[C:31]1B(O)O>>[CH3:1][C@H:2]1[NH:7][C@@H:6]([CH3:8])[CH2:5][N:4]([C:9]2[C:10]([O:28][CH3:29])=[CH:11][C:12]([O:26][CH3:27])=[C:13]([NH:15][S:16]([C:19]3[CH:24]=[CH:23][C:22]([C:31]4[S:30][CH:34]=[CH:33][CH:32]=4)=[CH:21][CH:20]=3)(=[O:18])=[O:17])[CH:14]=2)[CH2:3]1

Participants

3

Reactant 2

HCID 27339602-Thiopheneboronic acidHCID 69197436HCID 69197436, compound

Product 1

HCID 59007089HCID 59007089, compound

Procedure

The title compound (E244) was prepared from the product of Step 1 and 2-thienylboronic acid using a similar method to that described for Examples 237-243. MS (ES+) m/e 488 [M+H]+.

Sources & evidence

ORD record
ord-28cede099b85488ba96db4b1b7854d5c
Source dataset
uspto-grants-2008_06
Patent number
US07381728B2

Reaction notes

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