2-Thiopheneboronic acid → N-[5-Bromo-2-(methyloxy)phenyl]-4-(2-thienyl)benzenesulfonamide

HRID 130470Notes

Reaction equation

HRID 130470 reaction equation
[Br:1][C:2]1[CH:3]=[CH:4][C:5]([O:19][CH3:20])=[C:6]([NH:8][S:9]([C:12]2[CH:17]=[CH:16][C:15](I)=[CH:14][CH:13]=2)(=[O:11])=[O:10])[CH:7]=1.[S:21]1[CH:25]=[CH:24][CH:23]=[C:22]1B(O)O>>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([O:19][CH3:20])=[C:6]([NH:8][S:9]([C:12]2[CH:17]=[CH:16][C:15]([C:22]3[S:21][CH:25]=[CH:24][CH:23]=3)=[CH:14][CH:13]=2)(=[O:11])=[O:10])[CH:7]=1

Participants

3

Reactant 2

HCID 27339602-Thiopheneboronic acidHCID 47310943N-[5-Bromo-2-(methyloxy)phenyl]-4-iodobenzenesulfonamide

Product 1

HCID 69197888N-[5-Bromo-2-(methyloxy)phenyl]-4-(2-thienyl)benzenesulfonamide

Procedure

The title compound was prepared from the product of Step 1 and 2-thienylboronic acid using a similar method to that described for Examples 237-243 (E237-E243). MS (ES−) 422/424 [M−H]−.

Sources & evidence

ORD record
ord-bc91800008a743da9de3b6406c9cc9f4
Source dataset
uspto-grants-2008_06
Patent number
US07381728B2

Reaction notes

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