HuagongsheHuagongshe Chemistry Print Report · For research reference only
Fluoroacetyl chloride → HCID 25012029, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Fluoroacetyl chloride | HCID 9663 | — |
| Reactant | (1R,2S)-1-(4-ethylphenyl)-1-{[1-(4-fluorophenyl)-1H-indazol-5-yl]oxy}propan-2-amine | HCID 59339861 | — |
| Product | HCID 25012029 | HCID 25012029 | — |
Reaction Steps
Prepared as described in Example 1 using (1R,2S)-1-(4-ethylphenyl)-1-{[1-(4-fluorophenyl)-1H-indazol-5-yl]oxy}propan-2-amine (7a, 20 mg, 50 μmol) and fluoroacetyl chloride (14 mg, 150 μmol). Yield 15 mg (65%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07728030B2 |
| Source dataset | uspto-grants-2010_06 |
| ORD ID | ord-9b82c94e5efa431290f2ba60b7cc36a2 |
| Source note | uspto-grants-2010_06 |