HCID 57076224, compound → HCID 57300039, compound

HRID 130562Notes

Reaction equation

HRID 130562 reaction equation
[C:1]([O:5][C:6](=[O:19])[CH2:7][C@@H:8]([CH2:17][NH2:18])[CH2:9][C@H:10]([CH3:16])[CH2:11][CH2:12][CH2:13][CH2:14][CH3:15])([CH3:4])([CH3:3])[CH3:2].C(OC(=O)C[C@@H](CN=[N+]=[N-])C[C@@H](C)CCCCC)(C)(C)C>>[C:1]([O:5][C:6](=[O:19])[CH2:7][C@@H:8]([CH2:17][NH2:18])[CH2:9][C@@H:10]([CH3:16])[CH2:11][CH2:12][CH2:13][CH2:14][CH3:15])([CH3:2])([CH3:4])[CH3:3]

Participants

3

Reactant 2

HCID 57076224HCID 57076224, compoundHCID 57252745HCID 57252745, compound

Product 1

HCID 57300039HCID 57300039, compoundYield 72%

Procedure

A procedure similar to that used to prepare compound 161 was used except that (3S,5S)-3-Azidomethyl-5-methyl-decanoic acid tert-butyl ester 169 (2.50 g, 8.405 mmol) was used as a reactant to give 170 as an oil (1.648 g, 72%). MS (APCl) m/z 272 (M++1, 100%).

Sources & evidence

ORD record
ord-10db2fee68b84034a5f29e155b1969ec
Source dataset
uspto-grants-2008_06
Patent number
US07381747B2

Reaction notes

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