Hydrochloric Acid → HCID 59731059, compound

Participants

Reaction Steps

70 mg of methyl 5-methanesulfonyl-2-methyl-4-(4-pentafluorosulfanyl-phenylamino)benzoate were dissolved in 2 ml of MeOH, and 0.12 ml of a 2N aqueous NaOH solution was added. The mixture was stirred at RT for 2 h and then left to stand at RT for 16 h. The reaction mixture was then poured into 50 ml of water, adjusted to pH=2 with aqueous HCl solution and stirred at RT for 30 minutes, and finally the product was filtered off with suction. 66 mg of colorless crystals were obtained, mp 106-109° C.

Provenance & Evidence