Sodium Hydroxide → HCID 178463781, compound

HRID 130648Notes

Reaction equation

HRID 130648 reaction equation
[Br:1][CH2:2][CH2:3][N:4]([CH2:21][CH3:22])[C:5]1[CH:10]=[CH:9][C:8](/[N:11]=[N:12]/[C:13]2[CH:20]=[CH:19][C:16]([CH:17]=O)=[CH:15][CH:14]=2)=[CH:7][CH:6]=1.Cl.[CH3:24][N:25]1[C:29]([CH3:30])=[CH:28][S:27]/[C:26]/1=[N:31]\[NH2:32].[OH-].[Na+]>C(O)(=O)C.O>[CH3:24][N:25]1[C:29]([CH3:30])=[CH:28][S:27]/[C:26]/1=[N:31]\[N:32]=[CH:17][C:16]1[CH:19]=[CH:20][C:13](/[N:12]=[N:11]/[C:8]2[CH:9]=[CH:10][C:5]([N:4]([CH2:3][CH2:2][Br:1])[CH2:21][CH3:22])=[CH:6][CH:7]=2)=[CH:14][CH:15]=1

Participants

6

Reactant 3

HCID 14798Sodium HydroxideHCID 87580511HCID 87580511, compoundHCID 178463782HCID 178463782, compound

Product 1

HCID 178463781HCID 178463781, compound

Reagents, catalysts & solvents 2

HCID 176Acetic AcidSolventHCID 962WaterSolvent

Procedure

A mixture of 0.43 g of 4-((E)-{4-[(2-bromoethyl) (ethyl)amino]phenyl}diazenyl)benzaldehyde and 0.21 g of (2Z)-3,4-dimethyl-1,3-thiazol-2(3H)-one hydrazone hydrochloride in 10% acetic acid is stirred at room temperature for 60 minutes. Next, the preparation is diluted with 50 mL of water and cooled with ice. The reaction mixture is made neutral with 2N sodium hydroxide, then the precipitate that formed is suction filtered off, washed with water, and the product obtained is dried under vacuum.

Workup

  1. temperaturecooled with ice
  2. customthe precipitate that formed
  3. filtrationfiltered off
  4. washwashed with water
  5. customthe product obtained
  6. customis dried under vacuum

Sources & evidence

ORD record
ord-89b7c3479b8d4f4ab11d7880b20e3a0d
Source dataset
uspto-grants-2008_06
Patent number
US07381806B2

Reaction notes

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