HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Hydroxybenzaldehyde → 3-Chloro-4-(4-formylphenoxy)benzonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Hydroxybenzaldehyde | HCID 126 | — |
| Reactant | 3-Chloro-4-fluorobenzonitrile | HCID 145525 | — |
| Product | 3-Chloro-4-(4-formylphenoxy)benzonitrile | HCID 56851425 | 1.91% |
Reaction Steps
The above compound is prepared by nucleophilic displacement reaction of 4-hydroxy benzaldehyde and 3-chloro-4-fluorobenzonitrile under basic conditions as described in Example 243, step 1.91% yield.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07381719B2 |
| Source dataset | uspto-grants-2008_06 |
| ORD ID | ord-00ce6ab391e4482686748c3c97010fec |
| Source note | uspto-grants-2008_06 |